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Hypericum & Depression

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Study 22

Phytotoxicity caused by hypericum

AU:Siegers-C-P, Biel-S, Wilhelm-K-P

So: Nervenheilkunde 12(1993) 320-322

In this study the effect of different hypericum extracts on human keratinocytes radiated with UV-light was investigated.

The results imply that hypericum has no phytotoxic effect in antidepressant doses. Experience from animals and HIV experiments with hypericin indicate that phytotoxic effects might come in light-colored people when exposed to sunlight and a dose of hypericum 30-50 times higher than the antidepressant doses. There were big differences between different hypericum extracts concerning phytotoxicity, as seen in Figure 25.


Copyright © 1996 by Harold H. Bloomfield, M.D. and Peter McWilliams

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